Gender Pre-selection
Gender Selection:
Male Gender Pre-selection
Female Gender Pre-selection
The wish for an offspring of desired gender for many couples has been sought for many years. With the increasing treatment of artificial insemination and in-vitro fertilization for infertility patients, the desires to preselect the child gender is even higher due to their limitation on family growth. The prospect of a reliable isolation method for preconception gender preselection in humans has been researched for a long time. Any isolation method for separating X or Y-bearing chromosome must be performed on living sperm cells. These methods based on the DNA content and characteristic of the sperm: X-bearing sperm is 2.8% total DNA heavier than Y-bearing sperm and the fluorescent spot or F-body on the Y-bearing sperm.
Currently, there are many different method of sex preselection: Human Serum Albumin Gradients (HSA), Percoll Gradients, Sephendex columns, modified swim-up technique and recently MicroSort.
At our center, we provided the Human Serum Albumin (HSA) method for both Male and Female Gender Pre-selection. The isolation process is based on the ability of sperm to swim with difference degrees of velocity in albumin gradients. In general, a semen sample is washed and is layered over a solution of HSA in a series of columns. At a specific time of incubation, a portion of sperm which swim downward to a specific HSA gradient are collected and resuspended in a nutrient rich media for artificial insemination at the time of ovulation or for in-vitro fertilization procedure.
For any question or Gender Preselection consultation, please call us at 714-771-7800